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[[_TOC_]]
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### Assertion API
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### Assertion API for Richards et.al., 2015 ACMG specifications
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Assertion API endpoint for computing variant pathogenicity given a set of evidence counts and assertion criteria. The specification used here is based on _Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology_. Richards _et.al_ (<https://pubmed.ncbi.nlm.nih.gov/25741868/>). For ClinGen VCEP specific assertion criteria refer the CSpec Registry - <https://cspec.genome.network>
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| ... | ... | @@ -156,4 +156,6 @@ Assertion API endpoint for computing variant pathogenicity given a set of eviden |
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> serverCertCheck : false,
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> }
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> resp = await jsClient.doPost('/assertion', payload, reqConfig)
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> ``` |
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\ No newline at end of file |
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> ```
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### Assertion API for v4 ClinGen specifications ( to be published ) |
