ACTIONABILITY KNOWLEDGE REPOSITORY ACTIONABILITY CURATION INTERFACE
Update History
Condition: Carney Complex
Gene/Gene Panel: PRKAR1A
Context: Pediatric
Date
Status
Release
Outcomes-Interventions
Notes
2022/02/09
Released
1.0.4
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
Internal system migration associated with MONDO name addition.
Assertions
Gene Condition Pairs
Suggested Assertion
Final Assertion
PRKAR1A ⇔ 0008057 CARNEY COMPLEX, TYPE 1; CNC1
Strong Actionability
Strong Actionability
2022/02/09
Released (Under revision)
1.0.3
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
Assertions
Gene Condition Pairs
Suggested Assertion
Final Assertion
PRKAR1A ⇔ 0008057 CARNEY COMPLEX, TYPE 1; CNC1
Strong Actionability
Strong Actionability
2021/03/29
Released
1.0.3
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
Assertions
Gene Condition Pairs
Suggested Assertion
Final Assertion
PRKAR1A ⇔ 0008057 CARNEY COMPLEX, TYPE 1; CNC1
Strong Actionability
Strong Actionability
2021/01/06
Released (Under revision)
1.0.2
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
Added MONDO IDs.
2020/04/22
Released
1.0.2
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
Added MONDO IDs.
2020/04/22
Released (Under revision)
1.0.1
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
2020/04/06
Released
1.0.1
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
2020/04/06
Released (Under revision)
1.0.0
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
2020/01/31
Released
1.0.0
P
Morbidity and mortality from cardiac myxomas (GroupA)
Cardiac imaging to detect and guide excision of tumors (GroupA) 11CC
Morbidity from primary pigmented nodular adrenocortical disease (GroupA)
Biochemical and imaging surveillance to detect tumors and guide treatment (GroupA) 10CD
2019/11/07
In Preparation
N/A
We have begun assessment of the Pediatric context for this topic
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